The Evolutionary Network Study of tRNA Sequences
tRNA序列的进化网络研究

According to the different anticodons of tRNA sequences, 3420 tRNA sequences were divided into 21 groups, including 20 groups of amino acids and one group of Stop. Networks were constructed by the sequences similar degree, including one whole tRNAs network and 21 subnetworks. The average degree and the average clustering coefficient were calculated, as well as the average shortest path in different networks based on the different similar degree. After analyzing, comparing and discussing three important parameters in the different networks, on one hand, it is further indicated that the point mutation of tRNA sequences is the important evolutionary mechanism and the evolution of tRNA sequences approximately accorded with the neutral theory; on the other hand, it is also reflected that tRNA sequences have closer homologous relationships in the evolutionary history during the same groups of the amino acids and Stop, and they have the self-similarity property in the process of evolution.