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生物物理学报 2002
MASS SPECTROMETRY AND NUCLEAR MAGNETIC RESONANCE BECOME THE IMPORTANT METHODS TO STUDY BIOLOGICAL MACROMOLECULES--BRIEF INTRODUCTION OF THE CONTRIBUTIONS OF NOBLE PRIZE LAUREATES IN CHEMISTRY 2002
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Abstract:
The Noble prize in chemistry for 2002 is being shared between three scientists who have made brilliant contributions in two important fields: mass spectrometry(MS) and nuclear magnetic resonance (NMR). The laureates, John B. Fenn and Koichi Tanaka have developed the methods for identifying the mass of biological macromolecules by MS. Kurt Wüthrich has established a method for determining the 3D solution structures of proteins by NMR. Their remarkably scientific achievements are the milestones in the developments of MS and NMR, and have promoted greatly the further development of these two methods. Nowadays, MS and NMR have become the two of most powerful research techniques used to embrace the biological macromolecules.