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生物物理学报 2003
BIOPHYSICAL CHARACTERS OF CFU-E AND ITS DIFFERENTIATION
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Abstract:
Colony Forming Unit-Erythroids (CFU-Es) were obtained from mice during the acute disease caused by anemia-inducing virus (FVA). They were induced in medium which contains EPO, BSA, IL-3 and SCF. Their biophysical characters after 0, 12, 24 and 36 h and GATA-1 expression after 0, 12, 24 and 48 h were studied. The results showed that their biophysical characters were changed regularly, and that GATA-1 expressed abundantly until CFU-E has been induced for 48 h. After 48 h, content of GATA-1 became abruptly low.