BIDIRECTIONAL TRANSPORT OF APOLIPOPROTEIN E and LOW DENSITY LIPOROTEIN RECEPTORS IN THE PERIPHERAL NERVOUS SYSTEM
脱辅基脂蛋白E(ApoE)及低密度脂蛋白(LDL)受体在外周神经中的双向运输

In the present study, we used immunocytochemical method to investigate the properties of transportation of ApoE and LDL receptors in both normal and regenerated rat sciatic nerve. The results show that firstly, ApoE and LDL receptors can be transported bidirectionally (i.e. retro-and anterogr-adely) in the axoplasm along axons. Secondly, ApoE derived from regenerating fillers can be transported re t rogradely to the cell bodies. These results offer further evidence supporting the view that ApoE and LDL receptors participate in the repair and regeration following the nerve damage.