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生物工程学报 2009
Applications of nitrile converting enzymes in the production of fine chemicals
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Abstract:
Nitriles are an important type of synthetic intermediates in the production of fine chemicals because of their easy preparations and versatile transformations.The traditional chemical conversion of nitriles to carboxylic acids and amides is feasible but it requires relatively harsh conditions of heat,acid or alkali.Nitrile converting enzymes (nitrilase,nitrile hydratase and amidase) which are used as biocatalyst for the production of fine chemicals have attracted substantial interest because of their abilit...