Construction and immunogencity of recombinant adenoviruses expressing Cap protein of PCV2 and GP5 protein of PRRSV in mice
表达猪圆环病毒2型Cap和猪繁殖与呼吸综合征病毒GP5融合蛋白重组腺病毒的构建和免疫原性测定

Porcine circovirus 2(PCV2) has been implicated as the etiological agent of postweaning multisystemic wasting syndrome(PMWS).Co-infection of PCV2 and porcine reproductive and respiratory syndrome virus(PRRSV) can result in severe economic losses to the swine industry.In this study,we constructed the recombinant adenovirus rAd-Cap-GP5 expressing Cap of PCV2 and GP5 of PRRSV.And the expression of Cap and GP5 protein in the HEK-293 cells inoculated with rAd-Cap-GP5 were confirmed by immunoperoxidase monolayer a...