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生物工程学报 2009
Characterization and biocompatibility of human-like collagen-hyaluronic acid scaffold for blood vessel
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Abstract:
Human-like collagen (HLC) was cross-linked with hyaluronic acid by genipin in different ratio. The concentrations of hyaluronic acid in the mixture were 0,0.01%,0.05% and 0.1%. The blood vessel tubular grafts were then fabricated by freeze-drying. Microstructure,element composite,mechanical properties,cytotoxicity grade,and biocompatibility of different vascular scaffold groups were studied by scanning electron microscope (SEM),X-ray photoelectron spectroscopy (XPS),tensile test,burst pressure experiment,cy...