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ISSN: 2333-9721
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Engineering and metabolic characteristics of a Clostridium tyrobutyricum strain
酪丁酸梭菌代谢工程菌的构建及其发酵特性

Keywords: Clostridium tyrobutyricum,butyric acid,acetyl coenzyme A acetyltransferase,phosphotransacetylase,metabolic engineering
酪丁酸梭菌,丁酸,乙酰乙酰辅酶A转移酶,磷酸转乙酰基酶,代谢工程

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Abstract:

Clostridium tyrobutyricum is suitable for simultaneous saccharification and fermentation of lignocellulosic. It can produce butyric acid, acetic acid as its main fermentation products from a wide variety of carbohydrates such as glucose, xylose, cellobiose and arabinose. In order to decrease acetic acid content and increase butyric acid content in C. tyrobutyricum, we replaced genes on the acetic acid fermentation pathway with genes on the butyric acid fermentation pathway. Three genes were selected. They w...

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