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ISSN: 2333-9721
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Photodynamic effect of two kinds of phycobiliproteins on human liver cancer cell line SMMC-7721 in vitro
两种藻胆蛋白对人肝癌SMMC-7721细胞的光动力体外杀伤效应

Keywords: Porphyra yezoensis,R-phycoerythrin,C-phycocyanin,photodynamic therapy,cell apoptosis,liver cancer cell
条斑紫菜
,R-藻红蛋白,C-藻蓝蛋白,光敏作用,细胞凋亡,肝癌细胞

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Abstract:

We studied the effect of photodynamic therapy with phycobiliproteins on human liver cancer cells in vitro.With 3-(4,5-Dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide assay(MTT assay),we used two phycobiliproteins,R-phycoerythrin(R-PE) and C-phycocyanin(C-PC) prepared from Porphyra yezoensis,to determine the killing rates and apoptosis rates of human liver cancer cells(SMMC-7721) mediated by laser.When the concentration of R-PE was 120 mg/L,the survival rate of human liver cancer cells was 27% after tr...

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