Morphology and mechanical properties of normal lymphocyte and Jurkat revealed by atomic force microscopy
应用原子力显微镜分析正常淋巴细胞和Jurkat细胞的形态和机械性质

Alternations of lymphocyte in biophysical properties (e.g., morphology and viscoelasticity) are related to the human health, disease diagnosis and treatment. Here, we used atomic force microscopy (AFM) to characterize the morphology and mechanical properties of normal lymphocyte and Jurkat. The AFM images revealed that their cell shapes appeared similar. The mechanical properties of the two groups were tracked with AFM-based force spectroscopy. The normal lymphocyte cells had a high adhesion force distribut...