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生物工程学报 2009
Patterning different cells based on microfluidics and self-assembled monolayers
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Abstract:
The ability to pattern multiple cells through precise surface engineering of cell culture substrates has promoted the development of cellular bioassays,such as differentiation,interaction and molecular signaling pathways.There are several well developed ways to pattern cells.This report describes a method for patterning multiple types of cells based on microfluidics and self-assembled monolayers.We developed two types of micro-dam structures by soft-lithography to locate cells precisely and modified the sub...