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生物物理学报 2000
RESEARCH ON THE LOCALIZATION OF MAGNETIC SOURCESIN THE BRAIN
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Abstract:
The brain is often considered as an electromagnetic system on MEG/EEG studies. From quasistatic approximation of Maxwell's equations, it can be found that the relationship between the primary current density representing the cerebral neuron activities and magnetic field outside the head is linear. A general method, which can be used to locate the magnetic sources in the brain from spatio-temporal MEG data, is discussed. The method is based on maximum likelihood estimation, when the noise is Gaussian. Computer simulation using spherically symmetric conductor head model demonstrates that the method is effective. Considering the real head-shaped model, an approximate method based on the union of MEG and EEG data is also presented.