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生物物理学报 1992
EFFECTS OF MONOCULAR DEPRIVATION ON THE DISTRIBUTION AND NUMBER OF GABA-IMMUNOPOSITIVE NEURONS IN THE VISUAL CENTRE OF THE HAMSTER
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Abstract:
Physiological studies suggest that monocular deprivation results in an extensive reduction of the capability of the deprivation eye to activate visual cortical cells. The nature of the change taking place in the cortex is a subject of controversy. One line of evidence favours a redistribution of the excitatory terminals. The another suggests that the deprivation eye input is in some way suppressed, possibly by GABA-mediated intracortical inhidition. Morphological studies obtained contradictory results too on the controversy mentioned above.The present study indicated a marked change in the number and distribution of GABA-immunopOsi tive neurons in the visual centres of hamster after monocular deprivation. This change is displayed mainly in the visual cortex. It supports the viewpoint of redistribution.