STUDIES ON GASPHASE SOMKE-INDUCED CHANGES OF MEMBRANE BIOPHYSICAL CHARACTERS
吸烟气相物质引起膜的生物物理特性改变的研究

Gasphase smoke-induced changes of liposome memdrane fluidities was studied by spin labeling technique. The results show that membrane fluidities increase with increasing bubbling time of gasphase smoke through the suspension of liposomes. The effects of gasphase smoke on conformation changes of -SH binding sites on proteins of rat lung cell membranes were also studied. The results show that the ratio of S/W (strong modilized component/weak modilized component) decreases with increasing bubbling time of gasphase smoke through the suspension of rat lung cells. In other words, the degree of exposed binding sites of -SH on rat lung cell membranes increases with bubbling time of gasphase smoke through the suspension of the cells.