APPLICATION OF DECONVOLUTION IN THE RESEARCH OF LIGHT TRANSMITTING PROPERTY IN BIOLOGICAL TISSUES
反卷积在生物组织光传输特性研究中的应用

Many methods have been proposed to investigate light distribution in the bio -tissues irradiated by a beam of pencil light--point-spread function psf .A mong them,Monte Carlo method is the most effective and exact one.But all the e xisting methods depend on the exact determination of optical parameters of the b io-tissues.In this paper,bio-tissues are regarded as a linear space invarian t system,thus the light distribution in the bio-tissues of certain depth is th e convolution of incident light source and point-spread function of bio-tissue .On the contrary,if the light distribution in certain depth of the bio-tissue can be measured by experiment,one can obtain the psf by deconvolution of the s ource and the measured light distributions.Based on this consideration,a new m ethod to determine psf is proposed,and which is applied in reconstructing the p oint-spread function of two kinds of typical bio-tissues--porcine dermis and m uscle,and the corresponding point-spread functions are obtained.The results a re compared with those obtained by Monte Carlo method,which verified that the r econstructing method is effective tools to obtain the point-spread function of bio-tissue.The method proposed in this paper can be used in the research of li ght transmitting property of all bio-tissues,especially for the tissues whose optical parameters are unknown.