Study on DNA Dynamic Structural Feature Based on DNA-Protein Complex Crystal Data
基于蛋白质-DNA复合物晶体结构的DNA结构动力学特性研究

Based on protein-DNA complex crystal structural data in up-to-date Nucleic Acid Database,taking into account the sequence-dependent feature of DNA,the key parameters in DNA dynamic structural model,force constant matrix,were calculated for 10 dimers and 36 tetramers.The non-diagonal elements represent the correlation between the structural parameters.One can calculate structural features,for example,curvature and flexibility,for given sequence using improved dynamic structural model.