THE INTERSPIKE INTERVAL INCREASES GRADUALLY: WHY?
峰峰间期逐渐增大的动力学机制

A phenomenon that the interspike interval increases gradually in a burst has been observed in the rat injured sciatic nerve with 3 or 4 loose ligatures after the addition of 5 mmol/L ethylene glycol tetraacetic acid (EGTA). It is significant to make clear dynamical mechanism for the emergence of such a phenomenon for understanding neuronal complex discharge behavior. By the use of Hindmarsh-Rose neuron model, one possible mechanism is revealed from the perspective of nonlinear dynamics. Namely, it is saddle-node bifurcation and saddle-homoclinic orbit bifurcation that dominate this type of bursting, and the latter plays a more important role in leading to the gradual increase of the interspike interval