INTEGER MULTIPLE BURSTING GENERATED IN AN EXPERIMENTAL NEURAL PACEMAKER
实验性神经起步点产生的整数倍簇放电节律

The stochastic bursting generated in stochastic Hindmarsh-Rose model was an evidence for the existence of autonomous stochastic resonance (ASR) in neural systems. Unfortunately, it has not been observed in the experiment. Stochastic bursting pattern was found in the experiment on an experimental neural pacemaker perfused with solution whose extra-cellular calcium concentration (Ca2+].) was lower than that of period 1 spiking. The inter-burst intervals (IBIs) of the stochastic bursting exhibited multi-mode and were approximately integer multiples of a basic 767, similar to those of the ISIs of the integer multiple spiking caused by coherence resonance. The stochastic bursting generated in stochastic Hindmarsh-Rose model exhibited similar characteristics. The results verified the existence of the stochastic bursting caused by autonomous stochastic mechanism and revealed its statistical characteristics, hi addition, the parameter region of the stochastic bursting and its distinction to the integer multiple spiking were identified. The integer multiple bursting was generated in the parameter region where Ca2+]. was lower than that of the integer multiple spiking.