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THE EFFECT OF CHOLESTEROL ON THE STRUCTURE OF DPPC MULTILAYERS
胆固醇对二棕榈酰磷脂酰胆碱(DPPC)多层膜结构的影响

Keywords: Cholesterol,DPPC,x-ray diffraction DSC
胆固醇,二棕榈酰磷脂酰胆碱,X-射线衍射,差示扫描量热

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Abstract:

The effect of cholesterol on the stryctyre of dipalmitoylphosphatidyl-choline(DPPC)multilayers has been studied by SAXD(small angle x-ray diffraction) and DSC(differential scanning calorimetry)techniques. DSC thermograms showed that the sharp,highly cooperative phase transition in DPPC disappeared gradually with increasing of the cholesterol content.At a cholesterol concentration of 40(mol)% or more,a phase separation was observed in both x-ray diffraction and DSC experiment.

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