NONINVASION MEASURING MATHEMATICAL MODEL OF MYOCARDIAL INFACT SIZE
心肌梗塞面积无损计测数学模型

Dynamic and quantitative of measurement myocardial infarction "area" is beneficial to monitoring forecast, treatment and prognosis of the patients. There was a variety of methods measuring myocardial infarction "area" , but few of them suited to clinical medicine. The present paper analyzed the formation of eletric dipole layers on the infarction (ischemia, injury, necrosis) surfaces at the cardiac cell and membranes according to electric polarization theory from electrocardiodynamics and electrobiology, introduced the myocardial infarct vectors including ischemia, injury, and necrosis vectors and established the mathematical model of measuring myocardial infarction "area" for the first time. The features of the model are (1) the model was established on the tasis of thinking from origin to field. The electro-biology theory analysis on the origin was deeper, and the surveying method was more simple on the field as well as non-invasive; (2) by means of the model not only the sizes of the infarction area could be measured, but also the positions (frontal, frontoseptal, lateral, back and lower wall) and characteristics (subexoc-ardial, subendocardial and perforated) of the infarction area could be determined; (3) the animal and clinical experiment showed that there were significant positive correlation between the two results calculated measured r>0.90 (P>0.01) .