THE PREDICTION OF THE STRUCTURAL CLASS OF PROTEIN:APPLICATION OF THE MEASURE OF DIVERSITY
用离散量预测蛋白质的结构型

According to the concept that structural class of protein is mainly determined by its secondary structure sequence, the structural class of a protein can be predicted by using the increment of diversity between the protein and a set of standard set of proteins. The standard sources of diversity are respectively determined by the secondary structure parameters Nα,Nβ,Nβαβ,N(βαβ). The four increments of diversity between the measure of diversity D(Xα), D(Xβ), D(Xα/β), D(Xα+β) and a measure of diversity D(Xn) of a new protein (n) (in the 1998 test set and the 1995 standard set) are respectively calculated. The structural class of a protein is determined by the lowest increments of diversity. The average rates of correct prediction are 84.8% for standard set and 83.8% for test set.