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生物物理学报 1995
THE SPECIFIC BINDING OF C-REACTIVE PROTEIN WITH MODEL RECEPTOR
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Abstract:
C-reactive protein is one of the most characteristic proteins in the acute phase, which partcipates in the acute inflammatory reactions. The synthetic amphiphiphilic molecules were used as the membrane bound model rceptors of the C-anctive protein in the present work. The specific binding between C-reactive protein and the amphiphilic molecules was studied, which is the first step towards the two-dimensional crystallization of C-reactive protein on the lipid monolayer. The fluorescence spectra showed that the fluorescence intensity of C-reactive protein was decreased after spacifically binding with its receptors.