~(31)P NMR STUDY OF THE INTERACTION BETWEEN SURFACTANTS AND LIPOSOMES
表面活性剂与脂质体相互作用的~(31)P核磁共振研究

31P-NMR results revealed a restriction of the phospolipid polar headgroup motion in small sonicated lecithin vesicles by the action of Tween 80 or Triton X-100. This may be related to the inetraction between phosphate residue of phospholipid and the hydrated surface active molecules through H-bond.The results also displayed that the isotropic motion of phospholipid polar headgroup in large liquid-crystalline multilayered liposomes appears after the addition of Triton X-100 to the liposome dispersion,suggesting that Triton X-100 can induce the structure change in large liquid-crystalline bilayer system. Project supported by the Science Fund of the Chinese Academy of Sciences.