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生物工程学报 1998
Application of Infrared Spectroscopy to Monitoring the Bioprocesses
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Abstract:
On line measuring concentrations of chemical components is of fundamental importance in many bioprocesses.However,the on line measurement is very difficult to make for many analytical techniques because of the requiring sterilization of probes and the complexity of the bioprocesses.Rapid advances in instrumentation and data processing techniques in recent years have allowed infrared spectroscopy to be increasingly applied to in situ or on line monitoring bioprocesses.The basic principle and recent developments of infrared process analysis are introduced .In addition,the application of infrared spectroscopy in monitoring bioprocesses are reviewed.