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生物工程学报 2001
Advances in the Expression of Foreign genes in Hansenula Polymorpha
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Abstract:
Hansenula polymorpha\% is a potential host for foreign gene expression,which has been applied widely in academic studying and industry application.It has a number of advantages of expressing genes derived from eukaryotic organisms,such as mitotically stable recombinant strains,faithful processing of the produced polypeptides,and high productivity \%et al.\%Numerous foreign proteins with high commercial value have been expressed successfully in \%H.polymorpha,\%among which some have been launched on the market.In this review,the favorable characteristics of this system for foreign gene production and new advances are described.