Lithospermum erythrorhizon Cell Suspension Culture and Shikonin Derivatives Formation
硬紫草细胞悬浮培养和紫草宁及其衍生物的形成

In Lithospermum erythrorhizon cell suspension culture, the cell growth curve was a type of flat "S". After the growth of cells almost stopped, shikonin derivatives formed rapidly. The change of shikonin formation had negative relevance to that of cell growth. During the culture, the changes of the contents of soluble sugar and inorganic nurtients, DO and pH values of medium, and the morphology of cells were studied. The results could give an important reference for the large-scale cultures of Lithospermum erythrorhizon cells in future.