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PLOS ONE  2012 

Gene Expression Profiles of Colonic Mucosa in Healthy Young Adult and Senior Dogs

DOI: 10.1371/journal.pone.0012882

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Abstract:

We have previously reported the effects of age and diet on nutrient digestibility, intestinal morphology, and large intestinal fermentation patterns in healthy young adult and senior dogs. However, a genome-wide molecular analysis of colonic mucosa as a function of age and diet has not yet been performed in dogs.

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