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PLOS ONE  2012 

Causality in the Association between P300 and Alpha Event-Related Desynchronization

DOI: 10.1371/journal.pone.0034163

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Abstract:

Recent findings indicated that both P300 and alpha event-related desynchronization (α-ERD) were associated, and similarly involved in cognitive brain functioning, e.g., attention allocation and memory updating. However, an explicit causal influence between the neural generators of P300 and α-ERD has not yet been investigated. In the present study, using an oddball task paradigm, we assessed the task effect (target vs. non-target) on P300 and α-ERD elicited by stimuli of four sensory modalities, i.e., audition, vision, somatosensory, and pain, estimated their respective neural generators, and investigated the information flow among their neural generators using time-varying effective connectivity in the target condition. Across sensory modalities, the scalp topographies of P300 and α-ERD were similar and respectively maximal at parietal and occipital regions in the target condition. Source analysis revealed that P300 and α-ERD were mainly generated from posterior cingulate cortex and occipital lobe respectively. As revealed by time-varying effective connectivity, the cortical information was consistently flowed from α-ERD sources to P300 sources in the target condition for all four sensory modalities. All these findings showed that P300 in the target condition is modulated by the changes of α-ERD, which would be useful to explore neural mechanism of cognitive information processing in the human brain.

References

[1]  Linden DE (2005) The P300: where in the brain is it produced and what does it tell us? Neuroscientist 11: 563–576.
[2]  Comercheroa MD, Polich J (1999) P3a and P3b from typical auditory and visual stimuli. Clinical Neurophysiology 110: 24–30.
[3]  Polich J (2007) Updating P300: an integrative theory of P3a and P3b. Clinical neurophysiology 118: 2128–2148.
[4]  Zaslansky R, Sprecher E, Tenke CE, Hemli JA, Yarnitsky D (1996) The P300 in pain evoked potentials. PAIN 66: 39–49.
[5]  Hamalainen JA, Ortiz-Mantilla S, Benasich AA (2010) Source localization of event-related potentials to pitch change mapped onto age-appropriate MRIs at 6months of age. NeuroImage 54: 1910–1918.
[6]  Hillyard SA (2009) Imaging techniques: Event-related potentials (ERPs) and cognitive processing. New Encyclopedia of Neuroscience 30: 13–18.
[7]  Bledowski C, Prvulovic D, Hoechstetter K, Scherg M, Wibral M (2004) Localizing P300 generators in visual target and distractor processing: a combined event-related potential and functional magnetic resonance imaging study. The Journal of neuroscience 24: 9353–9360.
[8]  Hegerl U, Frodl-Bauch T (1997) Dipole source analysis of P300 component of the auditory evoked potential: a methodological advance? Psychiatry Research: Neuroimaging 74: 109–118.
[9]  Huster RJ, Westerhausen R, Pantev C, Konrad C (2010) The Role of the Cingulate Cortex as Neural Generator of the N200 and P300 in a Tactile Response Inhibition Task. Human Brain Mapping 31: 1260–1271.
[10]  Tarkka IM, Micheloyannis? S, Stokic? DS (1996) Generators for human P300 elicited by somatosensory stimuli using multiple dipole source analysis. Neuroscience 75: 275–287.
[11]  Ba?ar E, Ba?ar-Eroglu C, Karaka? S, Schürmann M (1999) Oscillatory Brain Theory A New Trend in Neuroscience. IEEE Engineering In Medicine and Biology 56–66.
[12]  Pfurtscheller G, Lopes da Silva FH (1999) Event-related EEG/MEG synchronization and desynchronization: basic principles. Clinical neurophysiology 110: 1842–1857.
[13]  Pfurtscheller G, Neuper C, Mohl W (1994) Event-related desynchronization(ERD) during visual processing. International Journal of Psychophysiology 16: 147–153.
[14]  Stan?ák A (2006) Cortical oscillatory changes occurring during somatosensory and thermal stimulation. Progress in Brain Research 159: 237–252.
[15]  Yordanova J, Kolev V, Polich J (2001) P300 and alpha event-related desynchronization (ERD). Psychophysiology 38: 143–152.
[16]  Ba?ar E, Ba?ar-Eroglu C, Karakas S, Schürmann M (2001) Gamma, alpha, delta, and theta oscillations govern cognitive processes. International Journal of Psychophysiology 39: 241–248.
[17]  Ba?ar E, Ba?ar-Eroglu C, Karakas S, Schürmann M (2000) Brain oscillations in perception and memory. International Journal of Psychophysiology 35: 95–124.
[18]  Klimesch W (1997) EEG-alpha rhythms and memory processes. International Journal of Psychophysiology 26: 319–340.
[19]  Schürmann M, Ba?ar E (1999) Event-related alpha oscillations in task processing. Clinical neurophysiology 110: 1784–1792.
[20]  Schürmann M, Ba?ar-Eroglu C, Ba?ar E (1997) A possible role of evoked alpha in primary sensory processing: common properties of cat intracranial recordings and human EEG and MEG. International Journal of Psychophysiology 26: 149–170.
[21]  Adrian ED, Mathews BHC (1934) The Berger rhythm: potential changes from the occipital lobes in man. Brain 57: 355–384.
[22]  John SB (1959) Rhythm activity induced by photic stimulation in relation to intrisic alpha activity of the brian in man. EEG Clin Neurophysiol 12: 317–326.
[23]  Yordanova J, Kolev V (1998) Event-related alpha oscillations are functionally associated with P300 during information processing. Neuro Report 9: 3159–3164.
[24]  Ku Y, Hong B, Gao X, Gao S (2010) Spectra-temporal patterns underlying mental addition: an ERP and ERD/ERS study. Neurosci Lett 472: 5–10.
[25]  Valentini E, Hu L, Chakrabarti B, Aglioti S, Hu Y, et al. (2012) The primary somatosensory cortex largely contributes to the early part of the cortical response elicited by nociceptive stimuli. Neuroimage 59: 1571–1581.
[26]  He B, Astonlfi LBF, Han YN, Yang L (2011) eConnectome: A MATLAB toolbox for mapping and imaging of brain functional connectivity. Journal of Neuroscience Methods 195: 261–269.
[27]  Zhang ZG, Chang CQ, Hu L, Hu Y, Hung Y (2010) A Kalman Smoother Approach for Estimating Time-varying Cortical Connectivity from High-density EEG: Simulation and Application. The 7th International Conference on Cognitive Science (ICCS2010).
[28]  Li YZ, Xu T, Wang LQ, Hu Y (2008) fMRI-constrained source analysis of visual P300 in Landolt ring task. Chinese Science Bulletin 53: 76–86.
[29]  Muller BW, Stude P, Nebel K, Wiese H, Ladd ME, et al. (2003) Sparse imaging of the auditory oddball task with functional MRI. Neuroreport 14: 1597–1601.
[30]  Mouraux A, Iannetti GD (2008) Across-trial averaging of event-related EEG responses and beyond. Magnetic resonance imaging 26: 1041–1054.
[31]  Mu Y, Fan Y, Mao LH, Han SH (2008) Event-related theta and alpha oscillations mediate empathy for pain. Brain Research 128–136.
[32]  Schürmann M, Ba?ar E (2001) Functional aspects of alpha oscillations in the EEG. International Journal of Psychophysiology 39: 151–158.
[33]  Polich J, Kok A (1995) Cognitive and biological determinants of P300. Biological Psychology 41: 103–146.
[34]  Sauseng P, Klimesch W (2008) What does phase information of oscillatory brain activity tell us about cognitive processes? Neuroscience & Biobehavioral Reviews 32: 1001–1013.
[35]  Hua KG, Oishi K, Zhang JY, Wakana S, Yoshioka T, et al. (2009) Mapping of Functional Areas in the Human Cortex Based on Connectivity through Association Fibers. Cereb Cortex 19: 1889–1895.
[36]  Kolev V, Yordanova J, Schürmann M, Ba?ar E (1999) Event-related alpha oscillations in task processing. Clinical Neurophysiology 110: 1784–1792.
[37]  Ba?ar E, Ba?ar-Eroglu C, Rahn E, Schürmann M (1991) Sensory and cognitive components of brain resonance responses: an analysis of responsiveness in human and cat brain upon visual and auditory stimulation. Acta Otolaryngol 491: 25–33.
[38]  Ba?ar E, Schürmann M, Ba?ar-Eroglu C, Karakap S (1997) Alpha oscillations in brain functioning: an integrative theory. Int J Psychophysiol 26: 5–29.
[39]  Lopes da Silva F, Pijn J, Velis D, Nijssen P (1997) Alpha rhythms: noise, dynamics and models. Int J Psychophysiol 26: 237–249.
[40]  Ba?ar E, Yordanova J, Kolev V, Ba?ar-Eroglu C (1997) Is the alpha rhythm a control parameter for brain responses? Biol Cybern 76: 471–480.
[41]  Palva S, Palva JM (2007) New vistas for a-frequency band oscillations. Trends Neurosci 30: 150–158.
[42]  Barry RJ, Kirkaikul S, Hodder D (2000) EEG alpha activity and the ERP to target stimuli in an auditory oddball paradigm. International journal of psychophysiology 39: 39–50.
[43]  Brandt ME, Jansen BH (1991) The relationship between prestimulus-alpha amplitude and visual evoked potential amplitude. Int J Neuroscience 61: 261–268.
[44]  Brandt ME, Jansen BH, Carbonari JP (1991) Pre-stimulus spectral EEG patterns and the visual evoked response. Electroencephalography and clinical neurophysiology 80: 16–20.
[45]  Rahn E, Basar E (1993) Prestimulus EEG-activity strongly influences the auditory evoked vertex response: a new method for selective averaging. The International journal of neuroscience 69: 207–220.
[46]  Rahn E, Basar E (1993) Enhancement of visual evoked potentials by stimulation during low prestimulus EEG stages. The International journal of neuroscience 72: 123–136.
[47]  Ba?ar E, Stampfer H (1985) Important associations among EEG-dynamics, event-related potentials, short-term memory and learning. Int J Neurosci 26: 161–180.
[48]  Barry R, Rushby J, Johnstone S, Clarke A, Croft R, et al. (2004) Event-related potentials in the auditory oddball as a function of EEG alpha phase at stimulus onset. Clin Neurophysiol 115: 2593–2601.
[49]  Jansen BH, Brandt ME (1991) The effect of the phase of prestimulus alpha activity on the averaged visual evoked response. Electroencephalography and clinical neurophysiology 80: 241–250.
[50]  Jasiukaitis P, Hakerem G (1988) The effect of prestimulus alpha activity on the P300. Psychophysiology 25: 157–165.
[51]  Ba?ar E, Ba?ar-Eroglu C, Rosen B, Schütt A (1984) A new approach to endogenous event-related potentials in man—relation between EEG and P300-wave. Int J Neuroscience 24: 1–21.
[52]  Polich J (1997) On the relationship between EEG and P300: individual differences, aging, and ultradian rhythms. Int J Psychophysiol 26: 299–317.
[53]  Brandt ME (1997) Visual and auditory evoked phase resetting of the alpha EEG. International journal of psychophysiology 26: 285–298.
[54]  Rémond A, Lesèvre N (1967) Variations in average visual evoked potential as a function of the alpha rhythm phase (“autostimulation”). Electroencephalogr Clin Neurophysiol Suppl 26: 42–52.
[55]  Klimesch W, Doppelmayr M, Russegger H, Pachinger T, Schwaiger J (1998) Induced alpha band power changes in the human EEG and attention. Neuroscience Letters 244: 73–76.
[56]  Bastiaansen BCM, Posthuma D, Groot PFC, Geus EJC (2002) Event-related alpha and theta responses in a visuo-spatial working memory task. Clinical neurophysiology 113: 1882–1893.
[57]  Inui K, Tran TD, Hoshiyama M, Kakigi R (2002) Preferential stimulation of Adelta fibers by intra-epidermal needle electrode in humans. Pain 96: 247–252.
[58]  Inui K, Tsuji T, Kakigi R (2006) Temporal analysis of cortical mechanisms for pain relief by tactile stimuli in humans. Cereb Cortex 16: 355–365.
[59]  Mouraux A, Iannetti GD, Plaghki L (2010) Low intensity intra-epidermal electrical stimulation can activate Aδ-nociceptors selectively. Pain 150: 199–207.
[60]  Treede RD, Lorenz J, Baumg?rtner U (2003) Clinical usefulness of laser-evoked potentials. Neurophysiol Clin 33: 303–314.
[61]  Kandel R, Schwartz JH, Jessell TM (2000) Principles of Neural Science, 4th ed. McGraw-Hill, New York.
[62]  Rogan JC, Keselman HJ, Mendoza JL (1979) Analysis of repeated measurements. British Journal of Mathematical and Statistical Psychology 32: 269–286.
[63]  Girden ER (1992) ANOVA: Repeated measures. Newbury Park, CA: Sage.
[64]  Delorme A, Makeig S (2004) EEGLAB: an open source toolbox for analysis of single-trial EEG dynamics including independent component analysis. Journal of neuroscience methods 134: 9–21.
[65]  Jung TP, Makeig S, Westerfield M, Townsend J, Courchesne E, et al. (2001) Analysis and visualization of single-trial event-related potentials. Hum Brain Mapp 14: 166–185.
[66]  Makeig S, Jung TP, Bell AJ, Ghahremani D, Sejnowski TJ (1997) Blind separation of auditory event-related brain responses into independent components. Proc Natl Acad Sci USA 94: 10979–10984.
[67]  Miltner W, Johnson R Jr, Braun C, Larbig W (1989) Somatosensory event-related potentials to painful and non-painful stimuli: effects of attention. Pain 38: 303–312.
[68]  Brookes MJ, Gibson AM, Hall SD, Furlong PL, Barnes GR (2005) GLM-beamformer method demonstrates stationary field, alpha ERD and gamma ERS co-localisation with fMRI BOLD response in visual cortex. NeuroImage 26: 302–308.
[69]  Gaetz W, Cheyne D (2006) Localization of sensorimotor cortical rhythms induced by tactile stimulation using spatially filtered MEG. NeuroImage 30: 899–908.
[70]  Iannetti GD, Hughes NP, Lee MC, Mouraux A (2008) Determinants of laser-evoked EEG responses: pain perception or stimulus saliency? Journal of neurophysiology 100: 815–828.
[71]  Pascual-Marqui RD, Michel CM, Lehmann D (1994) Low resolution electromagnetic tomography: a new method for localizing electrical activity in the brain. Int J Psychophysiol 18: 49–65.
[72]  Hoechstetter K, Berg P, Scherg M (2010) BESA Research Tutorial 4: Distributed Source Imaging.
[73]  Yang L, Liu ZM, Rios C, He B (2009) Imaging Alpha Signal Modulation Using an ICA-Based EEG Inverse Approach. IFMBE Proceedings 25: 493–495.
[74]  Mullen T (2010) Source Information Flow Toolbox (SIFT)-An Electrophysiological information flow toolbox for EEGLAB. Society for Neuroscience Conference, San Diego, CA, USA.
[75]  Granger CWJ (1969) Investigating causal relations by econometric models and cross-spectral methods. Econometrica 37: 424–438.
[76]  Baccala LA, Sameshima K (2001) Partial directed coherence: a new concept in neural structure determination. Biol Cybern 84: 463–474.
[77]  Durka PJ, Zygierewicz J, Klekowicz H, Ginter J, Blinowska KJ (2004) On the statistical significance of event-related EEG desynchronization and synchronization in the time-frequency plane. IEEE Trans Biomed Eng 51: 1167–1175.

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