TWO-STATE MODEL FOR DIRECTED MOTION OF BROWNIAN MOTOR
分子马达定向运动的两态模型

Asymmetric and periodic potential was used to describe the interaction between motor proteins and filaments that were periodic and polar. The current and effective potential in the two-state model were calculated. It was shown that the directed motion of motor protein was relevant to the effective potential. The slope of the effective potential corresponded to an average force. Therefore existence of the average force incarnated that detailed balance was broken in two-state transition. The curve of force-velocity theoretical relationship was also compared with the experimental data, it was qualitative tallied with the experiment.