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生物物理学报 2004
PHOTOACOUSTIC IMAGING WITH DECONVOLVING THE DETECTED SIGNALS OF SAMPLE BY THE DETECTED SIGNAL OF A POINT SOURCE
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Abstract:
Photoacoustic imaging is a potential novel medical imaging technique to image structures in biological tissue. In the current photoacoustic imaging, the photoacoustic signals detected by a wide-band ultrasonic transducer are deconvolved by the impulse response of the transducer to compute the projection of the optical absorption of the sample, and then reconstruct the optical absorption distribution. But it's difficult to get the exact impulse response of the transducer. A relationship between the projections, detected photoacoustic signals of sample and point source are presented, and the projection can be computed with deconvolving the detected signals of the sample by the detected signal of a point source directly, which can be measured by focusing the incident laser. Experiments demonstrate that the reconstructed images agree well with the original sample. The spatial resolution of the system reaches 0.3 mm.