STUDIES ON THE NERVE CELL AFFINITY OF POLY(3-HYDROXYBUTYRATE-CO-3-HYDROXYHEXANOATE)(PHBHH_X)
羟基丁酸酯和羟基己酸酯共聚物的神经亲和性研究

PHA is a kind of materials with excellent mechanical properties and complete biodegradability. PHBHHX, long chain and short chain monomer polymerized PHA, has a better tenacity and rigidity. In our experiment, Hela cells and fetal rat cerebral cortex nerve cells were cultured on PHBHHX respectively, and the nerve cell affinity of the materials were evaluated by measuring the water contact angle of the materials and the circular dichroism(CD) of proteins adsorbed on the materials. Results indicate that PHBHHX is one of the promising nerve restoring materials. DSC method was used to determine the melting point of the materials so that it will be convenient to process the materials later.