CHAOTIC CHARACTERISTIC OF BRAINSTEM INFORMATION CONDUCTIVE OBSTRUCTION IN INFANTILE SPASMS
婴儿痉挛症脑干信息传导障碍的混沌学研究

Infantile spasms(IS) is one of epilepsy in children with physical and intellective maldevelopment. Its pathogenesis is unknown. At present, one of concurrent hypothesis about the pathogenesis of IS is only that brainstem is the responsible structure of IS. But this hypothesis can not been proved by traditional neurophysiological method. In this study, the pathogenesis of IS is investigated with the point of view of information science, the pathogenesis of IS is that brainstem dysfunction results from neural information conductive obstruction in brainstem. The correlation dimension of auditory evoked brain waves are estimated and compared to judge information conductive function in brainstem. In contrast to temporal lobar epilepsy patients(TLEP), correlation dimension at the auditory area in infantile spasm group is obviously low. This result demonstrates that the information conductive obstruction exist in brainstem of infantile spasm patients.