The flexibility of sharply bent DNA
急剧弯曲DNA柔韧性的研究进展

DNA sharply bending is essential for gene regulation as well as the package of nucleosomes and viruses. The major process to study DNA instinctive flexibility is DNA cyclization assay. Up to date, many new models have been developed for DNA cyclization research. And the best one is the worm-like chain model. With the deep development in this field, there are lots of advanced progress in important parameters about DNA cyclization assay, factors that influence DNA cyclization and DNA sharp bending field.