EFFECTS OF GABA AND ITS ANTAGONIST BICUCULLINE APPLIED IN ONE HEMISPHERE ON THE ELECTRICALLY EVOKED RESPONSES OF VISUAL CORTICAL NEURONS OF THE OTHER HEMISPHERE IN IHE GOLDEN HAMSTER
在一侧视皮层施加GABA或其拮抗剂对另一侧神经元电诱发反应的影响

The responses of visual cortical neurons in one hemisphere to electrical stimulation of the other hemisphere were modified by application of the inhibitory neurotransmitter GABA or ist antagonist bicuculline (Bicu) on the other hemisphere in the golden hamster. Changes of the response could be detected in a) response latency, b) shift of the discharge peak in time domain, c) the maxmurn discharge rate, and d)the total number of spikes . When the product of the maximum discharge rate and the total number of spikes was taken as indication of the response strength ,then in most cases (72.2% ). GABA reduces the response strength , GABA caused the response to decrease in 16.7% of the cases . And the responses of the rest cased were not affected . On the other hand , Bicu cause an increase of the response strength in about half of the cases, a decrease of the response strength in 16.7% of the cases . And in the rest cases , the responses were not affected.