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生物物理学报 1990
THE VARIATION OF THE DYNAMICS OF MEMBRANES AND CELL BEHAVIOR WERE ARISED WHEN THE LIGANDS COMBINED WITH THE RECEPTORS OF CELL MEMBRANES
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Abstract:
The variation of the dynamics of membranes and behavior of cells were arised whenthe ligands combine with the receptors of cell membranes.In this paper) we studied the variation of thermodynamics, the change of order parameter and the varians of electric charges of cell membranes. We hope that the theory evidence will provided for the resistance of the exfoliation and metastasis of cancer cells by laminin.We got the results and learned that there are an effect of release of heat from membranes; an increase of membrane fluidity and a decrease of cell mobility after the laminin was interacted with the receptor on the membranes of liver ascites cancer cells, by the method of micro-measurement heat, the technique of ESR and Cell-electrophoresis respectively.These variation of the dynamics of membranes and behavior of cells turned out to the cancer-reversion advantage because these variations can inhibite the cancer growth and exfoliation-metastasis.