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生物物理学报 2008
A Study on Impedance Spectroscopy Measurement Characteristic of Breast Tissues Based on Electrical Impedance Scanningmily
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Abstract:
To research the influence on the breast tumors characteristic image of electrical impedance scanning (EIS) which was made by breast tissues impedance spectroscopy and the growth pattern of breast tumors, the impedance character of 40 malignant tumors, 34 benign tumors and some normal breast tissues from 69 patients undergoing breast surgery who had been examined by EIS and mammography screening were analyzed, with the ex vivo spectroscopy measurement. Primary ex vivo spectroscopy experiments showed that the resistivity of various breast tissue took the following pattern: adipose tissue>cancerous tissue>mammary gland and benign tumor tissue. Of the 39 patients with 40 malignant tumors, 24 showed bright spots, 11 showed dark area in EIS and 5 showed no specific image. Of all the 30 patients with 34 benign tumors were almost no specific abnormality shown in EIS results. There are significant differences in the electrical impedance properties between cancerous tissue and normal tissue. It showed up high or low electrical impedance characteristic in EIS images because malignant tumors soak different surrounding tissue and the conductivity between them was dissimilar clearly. Nevertheless, the difference of admittivity between benign tumors and their surrounding tissue was small and so there was no distinct image in EIS.