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生物物理学报 2009
Analysis of The Transmembrane Structure of The Receptor Protein AgrC in agr System of Staphylococcus aureus
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Abstract:
Activation of the agr system in Staphylococcus aureus is initiated by the binding of a specific autoinducing peptide (AIPs) to the extracellular domain of AgrC. Comparison of the AgrC-IV and AgrC-I sequences revealed a set of divergent residues in the region of the receptor's second extracellular loop that could be responsible. AgrC-II could be interacting in the region of the receptor's first or second extracellular loop with AIP II.