Microfluidic Technology for Cellular Microenvironment Simulation and Application Research
微流控技术对细胞微环境的模拟及应用研究

Cellular microenvironment, which is a complex integration of multiple factors, plays a key role in cells′ behavior and function. It is rather difficult for the traditional research method of cell biology to provide a similar in-vivo environment for cell growth in vitro, which results in the inconsistencies between the facts in vivo and the research findings in vitro. With the introduction of microfluidics into cell culture technology, microfluidics system make it possible to mimic in vivo microenvironment. This paper dealt with the important factors of microenvironment and its in-vivo features, and discussed the potentiality of microfluidics to establish and control the microenvironment in vitro. Based on the findings available, the prospect of microfluidics in cellular microenvironment was also made.