|
生物物理学报 2002
THE THEORETIC AND EXPERIMENTAL STUDY ON THE CHANGE OF EMG POWER SPECTRUM CAUSED BY MUSCLE ATROPHY
|
Abstract:
Aiming at non-invasive detection of muscle atrophy by EMG analysis, a mathematical model is constructed to study the change of EMG power spectrum after muscle atrophy, and also a rat's hindlimb unloading muscle atrophy experimental model is made to validate the results from mathematical analysis. Based on the decrease of cross-sectional area of muscle fiber and unloaded contraction of atrophic muscle, the mathematical correlation between muscle atrophy and change of EMG power spectrum is studied by center conductor model, its electrical circuit equations and EMG systematic linear model. By numeric simulation and animal experiment, the increase of EMG amplitude and the decrease of high frequency components of EMG power spectrum resulting from muscle atrophy are discovered. So the theoretic model analysis is consistent with the animal experimental results. This model can correctly explain the correlation between muscle atrophy and change of power spectrum. The change of EMG power spectrum caused by muscle atrophy will probably provide a new non-invasive detection method of atrophy.