Isolation of strains of actinomycetes from Jiaozhou Bay and their activities against pathogenic microorganisms
胶州湾放线菌的分离及其抗病原微生物的活性检测

We isolated 224 actinomycetes strainsfromsea mud samples and 32 strainsfromseawater samples of the Jiaozhou Bay,China,by usingthe spread method.The isolates were groupedinto 7 groups on basis of their morphological characteristics.Their antimicrobial activities were tested by using the cup-plate method,and the results showed that 7 % of the isolates were active againstStaphylococcus aureus,11 %againstSarcine lutea,10 %againstEscherichia coli,11 %againstBacillus pyocyaneus,2 % againstCandida albicans,5 %againstCryptococcus,6 %againstStreptomyces viridochromogenes,and 6 %againstMucor miehei.Twenty-two percent of isolates were active against at least one of the test organisms.Our data suggests that actinomycetes fromthe Jiaozhou Bay,China can produce various active metabolites against pathogenic microorganisms,which provids unique and plentiful sources to screen novel natural products for combating diseases in man.