Biochemical Alterations Due to Overcrowding Stress Induction in Healthy Albino Rats

Exposure to stressful situations is among the most common human experiences. This study investigated changes in some lipids and biochemical parameters in male albino rats fed with an ad libitum diet for 7 days. Biochemical parameters studied were glucose, cholesterol, HDL, LDL, triglyceride, uric acid, urea, creatinine, total protein, globulin, albumin, GPT and GOT. The mean weight of the animals at day 7 showed an insignificant increase in the stressed group compared with the mean weight at day 1st. Uric acid, urea and creatinine levels increased significantly (p<0.05) over the control. There were insignificant reductions in plasma HDL cholesterol, LDL cholesterol, total protein and globulin in the animals. Blood glucose, total cholesterol, triglyceride, albumin, GPT and GOT were also insignificantly increased. In conclusion, the present data indicate that the rats which exposed to overcrowding stress on a daily basis for a period of 7 days shown an increase in some biochemical parameters including lipids related parameters while some other parameters were reduced.