Butyrylcholinesterase Levels in Nubian and Saanen Goats in the Highlands of Mexico: Effect of the Organophosphate Fenthion after Topical Aplication

The main objective of this study was first to study the normal concentration of blood Butirylcholinesterase in Nubian and Saanen Goats. To determine serum cholinesterase (ChE) a kinetic method was used. Normal mean values of ChE in 40 Nubian non lactating goats was found to be 0.031±0.008 U mL-1 in 4 lactating Nubian goats butirylcholinesterase values was 0.031±0.008 U mL-1 and in four Saanen goats 0.036±0.008 U mL-1. When 10 mg kg-1 of Fenthion was applied topically in the dorsal lumbar area, it was observed that serum ChE plummeted presenting a decrease of 64.8% during the first 3 to six days post application 64.5%. Thereafter, normal values similar to those observed before medication, were recorded until 18 and 24 days post application. None of the animals medicated showed signs of toxicity.