Wound Healing Activities of Plantag major Leaf Extract in Rats

Four groups of adult male Sprague dawley rats each consist of six animals. All animals were experimentally wounded in the dorsal neck area. Wounds of Group I rats each was treated with blank Vaseline-jelly (control), whereas wounds of Group II and Group III animals were treated with 5 and 10% Vaseline (Plantago major aqueous leaf extract in Vaseline), respectively. Wounds of Group IV rats each was treated with commercial solcoseryl-jelly as reference. The effects of vehicles on the rate of wound healing were assessed. Wounds treated with 5 and 10% Vaseline and solcoseryl jelly significantly healed earlier and much faster as compared to wounds of control. These results strongly document the beneficial effects of plant extract for the acceleration of wound healing process.