Histopathologic Study of Satureja hortensis Extract on Cadmium Induced Hepatic Lesion in Rat

Cadmium is an ubiquitous environmental and occupational toxic metal concened with a variety of adverse effect. The present study was undertaken to evaluate the role of Satureja hortensis in alleviating the Cd induced biochemical cghanges in male rat. During the experiment, rats injected with Cd (3 mg kg-1) subcutaneously alone or with administration extract at different doses (100 and 200 mg kg-1) for 8 weeks. In Cd treated rats, the activities of Aspartate Transminase (AST), Alanine Transaminase (ALT) were significantly increased in serum. Administration of satureja extract along with cadmium significantly decreased the serum. Satureja extract at a dose of 200 mg kg-1 was highly effective when compared to other dose (100 mg kg-1).