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PLOS ONE  2012 

Snca and Bdnf Gene Expression in the VTA and Raphe Nuclei of Midbrain in Chronically Victorious and Defeated Male Mice

DOI: 10.1371/journal.pone.0014089

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Abstract:

Alpha-synuclein (α-Syn) is a small neuronal protein that has been found to be expressed throughout the brain. It has been shown that α-Syn regulates the homeostasis of monoamine neurotransmitters and is involved in various degenerative and affective disorders. There is indication that α-Syn may regulate expression of the brain-derived neurotropic factor (BDNF) which plays an important role in the mood disorders.

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