Synthesis and Characterization of Transition Metal Complexes of Chlorpromazine

The chlorpromazine (CP) complexes of the transition metal ions, Zn(II), Cd(II) and Hg(II), have been synthesized. The complexes have been characterized by their elemental analysis, molar conductivity, magnetic susceptibility, UV-Visible, IR and 1H-NMR data. The molecular formulations of the new mononuclear complexes have been found to be [ZnBr(C17H19ClN2S.HCl)2]Br, [CdBr(C17H19ClN2S.HCl)2]Br.H2O, [Cd(C17H19ClN2S.HCl)2]I2 and[HgBr((C17H19ClN2S.HBr)2]Br.2H2O, where the ligand chlorpromazine or CP = C17H19ClN2S. The complexes, [ZnBr(C17H19ClN2S.HCl)2]Br, [CdBr(C17H19ClN2S.HCl)2]Br.H2O, and [HgBr((C17H19ClN2S.HBr)2]Br.2H2O, behave in DMF solutions as 1:1 electrolytes while the other complex, [Cd(C17H19ClN2S.HCl)2]I2, shows an ionic ratio of 1:2 in solution. Molecular structures have been proposed showing a square pyramidal environment around each metal center with an sp3d hybridization for the five-coordinate complexes, [ZnBr(C17H19ClN2S.HCl)2]Br, [CdBr(C17H19ClN2S.HCl)2]Br.H2O, and[HgBr((C17H19ClN2S.HBr)2]Br.2H2O. In the four-coordinate [Cd(C17H19ClN2S.HCl)2]I2 complex, the Cd(II) center with an sp3 hybridization has a tetrahedral environment around it.