|
Computer simulation of a novel pharmaceutical silicon nanocarrierDOI: http://dx.doi.org/10.2147/NSA.S8378 Keywords: diatom, docking, artificial neural network, simulation, computerized methods Abstract: mputer simulation of a novel pharmaceutical silicon nanocarrier Other (4832) Total Article Views Authors: Saeed Soltani, Soroush Sardar, Sima Azadi Soror Published Date November 2010 Volume 2010:3 Pages 149 - 157 DOI: http://dx.doi.org/10.2147/NSA.S8378 Saeed Soltani, Soroush Sardari, Sima Azadi Soror Drug Design and Bioinformatics Unit, Medical Biotechnology Department, Biotechnology Research Center, Pasteur Institute of Iran, Tehran, Iran Abstract: We show the potential of the nanosilicon structure of the frustules of a typical diatom, Cymatopleura sp., as a new vehicle for drugs. The basic diatom nanostructure is a lattice of SiO2, and computerized methods in a dock project have identified the most likely and the best drug types to load into such a structure.
|