Musculoskeletal deformities and fractures in Parkinson’s disease

Musculoskeletal deformities and fractures in Parkinson’s disease Letter (526) Total Article Views Authors: Masroor S, Rana MA, Alenazi B Published Date December 2011 Volume 2011:1 Pages 12 - 12 DOI: http://dx.doi.org/10.2147/JPRLS.S37044 Sufian Masroor,1 M. A. Rana,2 Bashir Alenazi3 1McMaster University, Hamilton, Ontario, Canada; 2Parkinson’s Clinic of Eastern Toronto, Toronto, Ontario, Canada; 3Armed Forces Hospital, Riyadh, Saudi Arabia Parkinson’s disease (PD) is a neurodegenerative condition that is characterized by a variety of severely debilitating motor and non-motor symptoms. Further, an increased risk of skeletal deformities and fractures, conditions ranging from scoliosis to osteoporosis, is of noteworthy importance. Following are some of the skeletal deformities seen in PD. Scoliosis, a lateral curving of the spine, is more common in PD patients than in the general population. Although the exact relationship between scoliosis and PD is not clearly known, it has been suggested that scoliosis is closely related to the dopamine deficiency associated with PD. Several studies have noted that the direction of the spinal curvature is correlated with the laterality of the major signs and symptoms of PD.1 It has been suggested that patients may slowly develop a tendency to lean towards the affected lagging side of PD during walking. This may result in the curvature of the spine seen in scoliosis, although genetic, biomechanical, or hormonal factors may play a role as well. Post to: Cannotea Citeulike Del.icio.us Facebook LinkedIn Twitter Readers of this article also read: Stem cell horizons in intervertebral disc degeneration A study on stress and depression experienced by women IT professionals in Chennai, India Tachykinins and neurokinin receptors in bone marrow functions: neural-hematopoietic link Reducing infections through nanotechnology and nanoparticles The management of cornea blindness from severe corneal scarring, with the Athens Protocol (transepithelial topography-guided PRK therapeutic remodeling, combined with same-day, collagen cross-linking) Dementia in Parkinson’s disease – a comprehensive review Postural Hypotension in Parkinson’s disease Depression in Parkinson’s disease Restless legs syndrome Corrigendum