A multicenter investigation of OPTI-FREE(RM) RepleniSH(RM) multi-purpose disinfecting solution impact on soft contact lens patient comfort

multicenter investigation of OPTI-FREE(RM) RepleniSH(RM) multi-purpose disinfecting solution impact on soft contact lens patient comfort Original Research (4676) Total Article Views Authors: Glenn S Corbin, Linda Bennett, Louis Espejo, et al Published Date January 2010 Volume 2010:4 Pages 47 - 57 DOI: http://dx.doi.org/10.2147/OPTH.S7498 Glenn S Corbin1, Linda Bennett2, Louis Espejo3, Suzanne Carducci4, Andrew Sacco5, Robert Hannigan6, Stuart Schatz7 1Wyomissing Optometric Center, Wyomissing, PA, USA; 2Bellmont, MA, USA; 3Rockville, MD, USA; 4Gaithersburg, MD, USA; 5Vestal, NY, USA; 6Taunton, MA, USA; 7College Park, MD, USA Objective: Demonstrate that successful soft contact lens wearers using competitive multipurpose solutions report improvement in comfort with OPTI-FREE RepleniSH Multi-Purpose Disinfecting Solution (MPDS). Methods: This 30-day, multicentered, open-label study enrolled 109 eligible soft contact lens wearers using COMPLETE Multi-Purpose Solution (MPS) Easy Rub or ReNu MultiPlus MPS. The test solution (OPTI-FREE RepleniSH MPDS) was dispensed for use in place of habitual care solutions. Subjects assessed their experience with their habitual solution (baseline) and the test solution (Day 30) using Likert-style questions. Contact lens acuity and biomicroscopy findings were recorded at each visit. Results: The test solution was associated with a statistically significant improvement in instillation comfort (P = 0.02), end of day comfort (P < 0.0001), clear vision (P < 0.0001) and overall satisfaction (P < 0.001). Subjects reported the test solution enhanced their overall lens-wearing experience more effectively than their previous solution (P < 0.0001) and that they would continue test solution use after the study (P < 0.0001). Conclusions: The test solution was effective at improving comfort and overall contact lens experience compared to COMPLETE MPS Easy Rub or ReNu MultiPlus MPS in successful contact lens wearers. These results indicate that changing contact lens care solutions, even in successful lens wearers, may improve comfort and overall lens-wearing experience.