Enamel matrix protein derivatives: role in periodontal regeneration

amel matrix protein derivatives: role in periodontal regeneration Review (3072) Total Article Views Authors: Rathva VJ Published Date December 2011 Volume 2011:3 Pages 79 - 92 DOI: http://dx.doi.org/10.2147/CCIDE.S25347 Vandana J Rathva Department of Periodontics, KM Shah Dental College and Hospital, Sumandeep University, Gujarat, India Abstract: The role of regenerative periodontal therapy is the reconstitution of lost periodontal structures, ie, new formation of root cementum, periodontal ligament, and alveolar bone. The outcome of basic research has pointed to the important role of enamel matrix protein derivative (EMD) in periodontal wound healing. Histologic results from animal and human studies have shown that treatment with EMD promotes periodontal regeneration. Moreover, clinical studies have indicated that treatment with EMD positively influences periodontal wound healing in humans. The goal of this paper is to review the existing literature on EMD.